Open AccessJoint Effect of Hepatic Steatosis and Alanine Aminotransferase Within the Normal Range on Incident Ischemic Heart Disease: A Prospective Study in Koreans
Author(s) -
Dong-Hyuk Jung,
Yong-Jae Lee,
Byoungjin Park
Publication year - 2021
Publication title -
clinical interventions in aging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.184
H-Index - 76
eISSN - 1178-1998
pISSN - 1176-9092
DOI - 10.2147/cia.s301741
Subject(s) - steatosis , medicine , hazard ratio , proportional hazards model , confounding , prospective cohort study , diabetes mellitus , epidemiology , confidence interval , gastroenterology , endocrinology
Hepatic steatosis has been associated with some cardiovascular risks. Increased alanine aminotransferase (ALT) was suggested to be linked to endothelial dysfunction. We prospectively investigated the joint effect of hepatic steatosis and elevated ALT within the normal range on incident ischemic heart disease (IHD) risk as an extrahepatic complication.