Open Access<p>Comparative Performance of Creatinine-Based GFR Estimation Equations in Exceptional Longevity: The Rugao Longevity and Ageing Study</p>
Author(s) -
Mengjing Wang,
Xuying Sun,
Li Ni,
Minmin Zhang,
Jiaying Zhang,
Guoxin Ye,
Jin Li,
Xiaofeng Wang,
Jing Chen
Publication year - 2020
Publication title -
clinical interventions in aging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.184
H-Index - 76
eISSN - 1178-1998
pISSN - 1176-9092
DOI - 10.2147/cia.s250535
Subject(s) - medicine , renal function , longevity , kidney disease , cohort , proportional hazards model , creatinine , estimating equations , urology , gerontology , statistics , mathematics , maximum likelihood
Reduced kidney function has been associated with an increased risk for adverse outcomes. Accurate assessment of glomerular filtration rate (GFR) is key to diagnosis and management of kidney disfunction. Debate exists on the best GFR estimation equation for elderly people. This study aimed to compare the predictive validity and discriminative ability of four GFR equations in relation to 2-year and 6-year mortality in exceptional longevity (EL) (those over 95 years old with intact health) individuals and is an ideal model to address factors relating to life span and age-related diseases.