Open AccessBIRC7 is Beneficial for Melanoma Progression and Hypoxic Response
Author(s) -
Hang Xu,
Huazhen Liu,
Zi Li,
Qian Xu,
Nan Lin,
Xiaoyang Li
Publication year - 2022
Publication title -
clinical, cosmetic and investigational dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.73
H-Index - 35
ISSN - 1178-7015
DOI - 10.2147/ccid.s370969
Subject(s) - melanoma , medicine , hypoxia (environmental) , cancer research , chemistry , oxygen , organic chemistry
Cutaneous melanoma (CM) accounts for about 90% of all melanoma cases. HIF-1α overexpression is associated with poor prognosis in many cancers including CM. Hence, we characterized differentially expressed genes (DEGs) in the response of CM cells to normoxia and hypoxia.