Open AccessInhibition of miR-155 Attenuates CD14+ Monocyte-Mediated Inflammatory Response and Oxidative Stress in Psoriasis Through TLR4/MyD88/NF-κB Signaling Pathway
Author(s) -
Jiajie Li,
Yanmin Liu,
Yilin Cao,
Juanjuan Wang,
Xiongwen Zhao,
Juan-Juan Jiao,
Junqin Li,
Kaiming Zhang,
Guohua Yin
Publication year - 2022
Publication title -
clinical, cosmetic and investigational dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.73
H-Index - 35
ISSN - 1178-7015
DOI - 10.2147/ccid.s350711
Subject(s) - cd14 , monocyte , tlr4 , inflammation , psoriasis , nf κb , tumor necrosis factor alpha , signal transduction , cancer research , medicine , immunology , biology , receptor , microbiology and biotechnology
Previous studies showed the link of CD14 + monocytes to inflammation and oxidation in psoriasis. In the present study, we investigated the regulatory role of miR-155 in CD14 + monocyte function in psoriasis.