Open AccessIncreased Frequency of Circulating Classical Monocytes in Patients with Rosacea
Author(s) -
Cuie Gao,
Lan Ge,
Dewei Chen,
Mengjie Zhang,
Li Zhao,
Wenying Liu,
Shuguang Chen,
Juan Wang,
Cunjian Zhou,
Xingwang Zhao,
Shifei Li,
Zhiqiang Song,
Jian Li
Publication year - 2021
Publication title -
clinical, cosmetic and investigational dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.73
H-Index - 35
ISSN - 1178-7015
DOI - 10.2147/ccid.s336194
Subject(s) - rosacea , monocyte , ccr2 , medicine , peripheral blood mononuclear cell , chemokine , pathogenesis , tumor necrosis factor alpha , immunology , ccl2 , chemokine receptor , inflammation , acne , dermatology , biology , biochemistry , in vitro
Monocyte subsets, including classical, intermediate and non-classical monocytes, are involved in the pathogenesis of inflammatory or autoimmune diseases. The pathogenic role of monocytes in the peripheral blood mononuclear cells (PBMCs) of patients with rosacea remains unclear. This study aimed to assess frequencies of monocyte subsets in PBMCs from rosacea patients before and after clinical treatment.