Open AccessComparative Analysis of Hyaluronidase-Mediated Degradation Among Seven Hyaluronic Acid Fillers in Hairless Mice
Author(s) -
SeongSung Kwak,
Kwang Ho Yoon,
Jin Hee Kwon,
Won Hyoung Kang,
Chang-Hoon Rhee,
Gi-Hyeok Yang,
Deu John M. Cruz,
WooChan Son
Publication year - 2021
Publication title -
clinical, cosmetic and investigational dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.73
H-Index - 35
ISSN - 1178-7015
DOI - 10.2147/ccid.s300960
Subject(s) - hyaluronidase , hairless , filler (materials) , hyaluronic acid , chemistry , medicine , nuclear medicine , materials science , composite material , anatomy , biochemistry , enzyme
Hyaluronic acid (HA) is the most common injectable dermal filler used for soft-tissue augmentation, and can be removed non-surgically by directly injecting hyaluronidase. In this study, the hyaluronidase-mediated degradation of different types of HA fillers implanted subcutaneously at the back of hairless mice having filler residence time of four days or three months were compared.