Open AccessThe Role of TROP2 in BCC and Cutaneous SCC: A Clinical and Immunohistochemical Study
Author(s) -
Azza Gaber Antar Farag,
Hala Said El-Rebey,
Mohamed A. Shoeib,
Shimaa Mohammed Ahmed El-Fiky,
Mustafa Elsayed Elshaib,
Amal Farid Mostafa
Publication year - 2021
Publication title -
clinical, cosmetic and investigational dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.73
H-Index - 35
ISSN - 1178-7015
DOI - 10.2147/ccid.s299862
Subject(s) - immunohistochemistry , basal cell carcinoma , medicine , pathology , pathogenesis , skin cancer , tissue microarray , basal cell , cancer
Nonmelanoma skin cancer (NMSC) mainly includes basal (BCC) and squamous (SCC) cell carcinoma. Trophoblast cell-surface antigen2 (TROP2), a cell-signal transduction, is one of the tumor-related calcium signal transducer gene family. TROP2 was highly expressed in many cancers, however, its role in BCC and SCC has not yet been studied.