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Androgens acting through the androgen receptor play a crucial role in the pathogenesis of acne. This study aimed to identify whether two key genes ( CYP21A2 and CYP19A1 ) involved in the synthesis and metabolism of androgens were associated with Pillsbury III-IV severe acne vulgaris.

The Associations of Androgen-Related Genes CYP21A2 and CYP19A1 with Severe Acne Vulgaris in Patients from Southwest China