Open Access<p>Human Adipose-Derived Mesenchymal Stem Cells-Derived Exosomal microRNA-19b Promotes the Healing of Skin Wounds Through Modulation of the CCL1/TGF-β Signaling Axis</p>
Author(s) -
Guoxiu Cao,
Bei Chen,
Xian Zhang,
Hongyun Chen
Publication year - 2020
Publication title -
clinical, cosmetic and investigational dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.73
H-Index - 35
ISSN - 1178-7015
DOI - 10.2147/ccid.s274370
Subject(s) - microvesicles , mesenchymal stem cell , hacat , exosome , wound healing , microrna , microbiology and biotechnology , dermal fibroblast , paracrine signalling , skin repair , cancer research , fibroblast , medicine , chemistry , immunology , biology , in vitro , receptor , biochemistry , gene
Human adipose-derived mesenchymal stem cells (ADMSCs) with their secretory factors are able to induce collagen synthesis and fibroblast migration in the wound healing process. This study is launched to figure out the effect of human ADMSCs-derived exosomes on skin wound healing.