Open Access<p>Dynamic Contrast-Enhanced MRI Confirms Rapid And Sustained Improvement Of Rheumatoid Arthritis Induced By Tocilizumab Treatment: An Italian Multicentre Study</p>
Author(s) -
Marco A. Cimmino,
Monica Parodi,
Francesca Barbieri,
Stefano Bombardieri,
Giuseppe Zampogna,
Annamaria Iagnocco,
Alberto Batticciotto,
Luca Maria Sconfienza,
Luigi Sinigaglia,
Fabrizio De Benedetti,
Fabiola Atzeni,
Piercarlo SarziPuttini
Publication year - 2020
Publication title -
biologics
Language(s) - English
Resource type - Journals
eISSN - 1177-5491
pISSN - 1177-5475
DOI - 10.2147/btt.s209873
Subject(s) - medicine , synovitis , rheumatoid arthritis , tocilizumab , magnetic resonance imaging , wrist , nuclear medicine , edema , surgery , radiology
This open-label study evaluated the effects of combined tocilizumab (TCZ) and disease-modifying antirheumatic drugs (DMARDs) on magnetic resonance imaging (MRI) changes in synovial membrane enhancement, bone marrow edema (BME), and erosions in the wrist and hand joints of rheumatoid arthritis (RA) patients inadequately responding to DMARDs alone.