Open AccessIs Routine Intraoperative Frozen Section Analysis of Sentinel Lymph Nodes Necessary in Every Early-Stage Breast Cancer?
Author(s) -
Bhoowit Lerttiendamrong,
Nattanan Treeratanapun,
Voranaddha Vacharathit,
Kasaya Tantiphlachiva,
Phuphat Vongwattanakit,
Sopark Manasnayakorn,
Mawin Vongsaisuwon
Publication year - 2022
Publication title -
breast cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.19
H-Index - 27
ISSN - 1179-1314
DOI - 10.2147/bctt.s380579
Subject(s) - medicine , frozen section procedure , breast cancer , axillary lymph node dissection , sentinel lymph node , lymphovascular invasion , sentinel node , stage (stratigraphy) , radiology , biopsy , surgery , lymph , surgical oncology , grading (engineering) , cancer , metastasis , pathology , civil engineering , engineering , biology , paleontology
Clinical application of the ACOSOG Z0011 trial results allows clinically node-negative breast cancer patients who meet criteria to avoid axillary dissection even when 1-2 sentinel lymph nodes (SLNs) are positive for metastatic disease. Intraoperative frozen section (iFS) analyses of SLNs were thought to reduce re-operation rates despite variable reported sensitivity and possibility of a false negative result. This study evaluated the rate of re-operations prevented by SLN iFS in a tertiary care hospital in Bangkok, Thailand, over a 6-year time-frame.