Open AccessCysteine Cathepsins and Matrix Metalloproteases Among Breast Cancer Patients
Author(s) -
Solomon Tsegaye,
Mohammed Mehdi,
Wajana Lako Labisso,
Daniel Seifu Melka
Publication year - 2021
Publication title -
breast cancer
Language(s) - English
Resource type - Journals
ISSN - 1179-1314
DOI - 10.2147/bctt.s305387
Subject(s) - proteases , cathepsin , extracellular matrix , breast cancer , matrix metalloproteinase , medicine , zymography , metastasis , cancer , pathology , surgical oncology , protease , cancer research , biology , enzyme , biochemistry
Cellular proteases are thought to increase the likelihood of cancer cell infiltration and metastasis by degrading constituents of the extracellular matrix (ECM). Measuring activities of these proteases may be used as tumor markers for early diagnosis, prognosis, and as a possible target for treatment plan.