Open AccessUrinary ATP may be a biomarker for bladder outlet obstruction and its severity in patients with benign prostatic hyperplasia
Author(s) -
Zhenghao Chen,
Yaxiao Liu,
Mengmeng Zhao,
Shulu Zu,
Yan Li,
Benkang Shi,
Shaoyong Wang,
Xiulin Zhang
Publication year - 2020
Publication title -
translational andrology and urology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.721
H-Index - 27
eISSN - 2223-4691
pISSN - 2223-4683
DOI - 10.21037/tau.2020.02.18
Subject(s) - urology , asymptomatic , urinary system , urine , medicine , hyperplasia , biomarker , receiver operating characteristic , urinary bladder , creatinine , bladder outlet obstruction , gastroenterology , chemistry , prostate , cancer , biochemistry
Urothelial cells release ATP into the urine in response to bladder stretch. Urinary ATP concentration in benign prostatic hyperplasia (BPH) patients was higher compared with asymptomatic controls. In this study, we aimed to explore the possibility that the urinary ATP level could be a non-invasive biomarker for bladder outlet obstruction (BOO) and its severity in BPH patients.