Open AccessComparison between sodium iodate and lipid peroxide murine models of age-related macular degeneration for drug evaluation—a narrative review
Author(s) -
SooYoung Kim,
Haohua Qian
Publication year - 2022
Publication title -
annals of eye science
Language(s) - English
Resource type - Journals
ISSN - 2520-4122
DOI - 10.21037/aes-21-25
Subject(s) - macular degeneration , drusen , retinal pigment epithelium , retinal degeneration , choroidal neovascularization , retinal , genetically modified mouse , medicine , pathology , biology , transgene , ophthalmology , biochemistry , gene
In this review, non-transgenic models of age-related macular degeneration (AMD) are discussed, with focuses on murine retinal degeneration induced by sodium iodate and lipid peroxide (HpODE) as preclinical study platforms.