Open AccessDirect-acting oral anticoagulants versus warfarin in relation to risk of gastrointestinal bleeding: a systematic review and meta-analysis of randomized controlled trials
Author(s) -
Mark M. Aloysius,
Abhilash Perisetti,
Hemant Goyal,
Umesha Boregowda,
Mladen Jecmenica,
Mahesh Cheryala,
Archna Bajaj,
Bojana Milekić,
Miloš Babić,
Pardeep Bansal,
Greg H. Enders
Publication year - 2021
Publication title -
annals of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.886
H-Index - 33
eISSN - 1792-7463
pISSN - 1108-7471
DOI - 10.20524/aog.2021.0658
Subject(s) - medicine , warfarin , dabigatran , rivaroxaban , relative risk , gastrointestinal bleeding , confidence interval , clinical endpoint , randomized controlled trial , atrial fibrillation
Direct-acting oral anticoagulants (DOACs) are increasingly used, with studies showing a lower risk of gastrointestinal bleeding (GIB), but overall data for GIB risk remains debatable. The objective was to assess non-fatal and fatal GIB risk in patients on DOACs compared with warfarin from randomized clinical trials (RCTs).