Open AccessPostoperative outcomes after preoperative ustekinumab exposure in patients with Crohn’s disease: a systematic review and meta-analysis
Author(s) -
Rajat Garg,
Babu P. Mohan,
Suresh Ponnada,
Miguel Regueiro,
Amy L. Lightner,
Benjamin Click
Publication year - 2021
Publication title -
annals of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.886
H-Index - 33
eISSN - 1792-7463
pISSN - 1108-7471
DOI - 10.20524/aog.2021.0634
Subject(s) - medicine , ustekinumab , crohn's disease , meta analysis , surgery , confidence interval , sepsis , complication , adverse effect , antibiotic prophylaxis , disease , antibiotics , infliximab , microbiology and biotechnology , biology
Recent studies have reported conflicting data on the risk of postoperative complications in patients with Crohn's disease (CD) exposed to ustekinumab (UST) preoperatively. We performed a systematic review and meta-analysis to better assess and quantify the risk of postoperative complications in this population undergoing major abdomino-pelvic surgery.