Open AccessComparative effectiveness of 5-hydroxytryptamine 3 receptor antagonists in irritable bowel syndrome: a network meta-analysis of randomized controlled studies
Author(s) -
Theodore Rokkas,
Konstantinos Ekmektzoglou,
Yaron Niv
Publication year - 2021
Publication title -
annals of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.886
H-Index - 33
eISSN - 1792-7463
pISSN - 1108-7471
DOI - 10.20524/aog.2021.0619
Subject(s) - medicine , irritable bowel syndrome , randomized controlled trial , placebo , meta analysis , cochrane library , ondansetron , pharmacology , nausea , alternative medicine , pathology
There is evidence demonstrating the beneficial effects of 5-hydroxytryptamine 3 receptor antagonists (5-HT 3 ) for the treatment of non-constipated irritable bowel syndrome (NC-IBS). We aimed to determine the comparative effectiveness of 5-HT 3 antagonists in NC-IBS, as evidenced by the results of a network meta-analysis (NWM) of published relevant randomized controlled trials (RCTs).