Open AccessRectal versus intramuscular diclofenac in prevention of post-endoscopic retrograde cholangiopancreatography pancreatitis: experience of a Greek tertiary referral center
Author(s) -
Ioannis Kalantzis,
Androniki Poulou,
Αθανάσιος Παπαθεοδώρου,
Konstantinos Gkoumas
Publication year - 2020
Publication title -
annals of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.886
H-Index - 33
eISSN - 1792-7463
pISSN - 1108-7471
DOI - 10.20524/aog.2020.0487
Subject(s) - medicine , diclofenac , endoscopic retrograde cholangiopancreatography , pancreatitis , odds ratio , incidence (geometry) , confidence interval , intramuscular injection , surgery , risk factor , gastroenterology , anesthesia , physics , optics
Independent patient-related and procedure-related factors increase the risk of pancreatitis after endoscopic retrograde cholangiopancreatography (post-ERCP pancreatitis [PEP]). Non-steroidal anti-inflammatory drugs (NSAIDs) have demonstrated efficacy in reducing the incidence of PEP. This study investigated the difference in the incidence of PEP between intramuscular and rectal prophylactic administration of diclofenac before ERCP.