Open AccessPrevalence De L’anemie Et Des Anticorps Specifiques Anti-P. Falciparum Chez Les PVVIH Et Co-Infectees Par Le Plasmodium Falciparum Au Congo-Brazzaville
Author(s) -
S. Judith Gbenoudon Satoguina,
Ruphin Bolanga,
Etienne Mokondjimobé,
Comlan de Souza
Publication year - 2016
Publication title -
european scientific journal
Language(s) - English
Resource type - Journals
eISSN - 1857-7881
pISSN - 1857-7431
DOI - 10.19044/esj.2016.v12n33p124
Subject(s) - coinfection , malaria , plasmodium falciparum , biology , antibody , virology , immunology , human immunodeficiency virus (hiv) , anemia , antiretroviral treatment , antiretroviral therapy , medicine , viral load
HIV and P. falciparum lead to diseases with overlapping endemic areas. Both diseases are leading cause of nearly 2 millions of deaths each year, which occur mostly in developing countries. People living with HIV are more susceptible to disease progressions. It is therefore important to further understand the biology of HIV and P. falciparum coinfection. The present study sets to characterize the coinfection with regard to malaria specific antibodies and to anemia. We found that antibody and hemoglobin levels as well as CD4 counts differ significantly according to parasite load and to treatment with anti retroviral. People undergoing treatment with antiretroviral, produced specific antimalarial IgG compared to their treatment naïve counterparts.