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Measurement of high concentrations of urine catecholamines and metanephrines is useful in diagnosing pheochromocytoma in humans. Stress increases catecholamine excretion in urine.

Urinary Catecholamine and Metanephrine to Creatinine Ratios in Healthy Dogs at Home and in a Hospital Environment and in 2 Dogs with Pheochromocytoma