Open AccessEtiо pathogenesis of spontaneous abortion
Author(s) -
О. N. Arganova,
Н. Г. Кошелева
Publication year - 2004
Publication title -
žurnalʺ akušerstva i ženskihʺ boleznej
Language(s) - English
Resource type - Journals
eISSN - 1684-0461
pISSN - 1683-9366
DOI - 10.17816/jowd87126
Subject(s) - medicine , abortion , placenta , placental insufficiency , endocrine system , myometrium , pregnancy , pathogenesis , obstetrics , fetus , gynecology , immunology , uterus , endocrinology , hormone , biology , genetics
One studied immunologic and genetic aspects of spontaneous abortion and the placenta insufficiency role in this pathology. It was determined, that increasing the production of cytokines by placenta's macrophages through something leads to increasing the reduced myometrium activity. Under cariotyping husbands and wives had spontaneous abortions on early terms it was found various genic and endocrine disturbtions. Modern topic diagnostics and algorithm of pregnancy observation with consideration of spontaneous abortion etiopathogenesis, treatment and placenta insufficiency prophylactics have permitted in most cases (more 93%) to give normal term of birth, to decrease perinatal losses.