Open AccessPostmortem diagnosis of shock conditions
Author(s) -
Акимов Павел Акимович,
Терехина Наталья Александровна
Publication year - 2015
Publication title -
kazanskij medicinskij žurnal
Language(s) - English
Resource type - Journals
eISSN - 2587-9359
pISSN - 0368-4814
DOI - 10.17750/kmj2015-775
Subject(s) - protamine sulfate , fibrinogen , shock (circulatory) , medicine , anaphylaxis , fibrin , etiology , forensic pathology , anesthesia , gastroenterology , protamine , autopsy , immunology , heparin , allergy
Aim. Develop a method for postmortem diagnosis of shock conditions.
Methods. Brood serum obtained from 72 dead bodies of people who died from different causes such as anaphylaxis, toxic shock, cardiovascular diseases, traumatic injury and thermal burns was examined. The level of fibrinogen fraction was performed by sulfite-alkaline method. Plasma soluble fibrin monomer complexes were identified by paracoagulation tests (ethanol and protamine sulfate tests).
Results. The method of shock conditions postmortem diagnosis was determined, regardless of shock etiology. The lowest levels of fibrinogen fraction in cases of anaphylactic and toxic shock were 19.3 and 11.9 g/l, respectively, which is significantly higher compared to other groups. In cases of death due to acute burn, fibrinogen level was almost tenfold higher (p