Open AccessThe newly synthesized 2-(3-hydroxy-5-methoxyphenyl)-6,7-methylenedioxyquinolin-4-one triggers cell apoptosis through induction of oxidative stress and upregulation of the p38 MAPK signaling pathway in HL-60 human leukemia cells
Author(s) -
Yung Yi Cheng,
Jai Sing Yang,
Shih Chang Tsai,
Chih Chuang Liaw,
Jing Gung Chung,
Li Jiau Huang,
Kuo Hsiung̀ Lee,
ChiCheng Lu,
Hsi Cheng Chien,
Minoru Tsuzuki,
Sheng Chu Kuo
Publication year - 2012
Publication title -
carolina digital repository (university of north carolina at chapel hill)
Language(s) - English
DOI - 10.17615/byqw-wh90
Subject(s) - oxidative stress , downregulation and upregulation , apoptosis , p38 mitogen activated protein kinases , microbiology and biotechnology , mapk/erk pathway , signal transduction , chemistry , biology , biochemistry , gene