Open AccessDoege-Potter Syndrome: A Presumptive Case of Metastatic Hemangiopericytoma with Persistent Hypoglycemia in a 27-Year-Old Male
Author(s) -
Von Lovel Zarra,
Kenny Jun Demegillo,
May Uyking-Naranjo,
Ahmad Domado
Publication year - 2021
Publication title -
journal of the asean federation of endocrine societies
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.153
H-Index - 3
eISSN - 2308-118X
pISSN - 0857-1074
DOI - 10.15605/jafes.036.01.16
Subject(s) - medicine , hypoglycemia , hemangiopericytoma , solitary fibrous tumor , insulin , endocrinology , pediatrics , pathology , stem cell , biology , cd34 , genetics
Doege-Potter syndrome (DPS) is a rare paraneoplastic condition characterized by hypoinsulinemic hypoglycemia from a solitary fibrous tumor. The underlying mechanism is the secretion of a prohormone form of insulin-like growth factor II (IGF-II) by the tumor, which causes decreased release of glucose into the circulation. We report the case of a 27-year-old Filipino male with presumptive DPS from a recurrent right temporo-zygomatic hemangiopericytoma (HPC). The complexity of DPS requires a multidisciplinary approach. Early screening for metastases from HPC may prevent the undesirable sequelae of the disease process.