Open AccessMicrobiome modulation in the prevention and management of colorectal cancer: a systematic review of clinical interventions
Author(s) -
Teodora D. Fratila,
Abdulrahman Ismaiel,
Dan L. Dumitraşcu
Publication year - 2022
Publication title -
medicine and pharmacy reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.35
H-Index - 16
eISSN - 2668-0572
pISSN - 2602-0807
DOI - 10.15386/mpr-2526
Subject(s) - medicine , colorectal cancer , probiotic , gut flora , microbiome , cancer prevention , fusobacterium nucleatum , carcinogenesis , cancer , oncology , bioinformatics , gastroenterology , immunology , biology , bacteria , periodontitis , porphyromonas gingivalis , genetics
The role of probiotics/prebiotics in modulating the procarcinogenic effects of microbiota have been studied with inconclusive results. This systematic review aimed to identify the role of several studied interventions on the gut microbiota modulation in humans for the prevention and management of colorectal cancer (CRC).