Open AccessPrimary non-Hodgkin diffuse large B-cell lymphoma of the lacrimal sac: a rare case of aggressive tumor and literature review
Author(s) -
Maria Gabriella Malzone,
Marzio Di Meglio,
Dario Furgiuele,
Nicola Galantuomo,
Sabrina Alfano,
Gennaro Mossetti
Publication year - 2021
Publication title -
medicine and pharmacy reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.35
H-Index - 16
eISSN - 2668-0572
pISSN - 2602-0807
DOI - 10.15386/mpr-1926
Subject(s) - medicine , lymphoma , radiation therapy , diffuse large b cell lymphoma , lacrimal sac , biopsy , non hodgkin's lymphoma , lacrimal apparatus , radiology , lacrimal gland , pathology
Primary malignant lymphomas of the lacrimal sac are rare neoplasms. They are mainly B-cell lymphoma with nonspecific and atypical symptoms, which can lead to misdiagnosis and a delay in the appropriate cure. Early diagnosis made by biopsy and the right choice of treatments can increase the chance of survival. We report a case of a non-Hodgkin diffuse large B-cell lymphoma (DLBCL) of the lacrimal sac, involving also the drainage system, in a 77-year-old female. She presented with an epiphora, swelling and a heavy visual impairment at the left eye successfully treated with cycles of polychemotherapy and radiotherapy.