Open AccessBiofilm formation in cutaneous wounds and its behavior in the face of interventions: an integrative review
Author(s) -
Eline Lima Borges,
Josimare Aparecida Otoni Spira,
Gilmara Lopes Amorim,
Ana Carolina Silva Martins Coelho
Publication year - 2022
Publication title -
rev rene
Language(s) - English
Resource type - Journals
eISSN - 2175-6783
pISSN - 1517-3852
DOI - 10.15253/2175-6783.20222378112
Subject(s) - psychological intervention , biofilm , scopus , medline , medicine , cochrane library , web of science , nursing interventions classification , nursing , meta analysis , pathology , biology , bacteria , biochemistry , genetics
Objective: to identify in the literature the biofilm formation and its behavior when faced with interventions in cutaneous wounds. Methods: an integrative review, carried out in the Cumulative Index to Nursing and Allied Health Literature, Latin American and Caribbean Health Sciences Literature, EMBASE, Scopus, The Cochrane Library Collaboration, MEDLINE/PubMed and Science Direct databases, without temporal delimitation. Nineteen studies were selected. The information was evaluated descriptively, comparing it with the pertinent findings. Results: the sample studies were published in English and included three types of biofilm research: two clinical, six in vitro and 11 in vivo (animal). Three themes were included: biofilm model creation (n=4), biofilm assessment (n=3), biofilm behavior before interventions for its management (n=12). Conclusion: the detrimental effects of biofilm on wound healing have been confirmed. Several interventions were able to reduce and eliminate biofilm in in vitro and in vivo models. Contributions to practice: it was found that clinical evaluation of the lesion does not allow the identification of biofilm, even when present; it is below the surface of the lesion. This finding raises reflection on the part of nurses regarding the interventions adopted for the removal of biofilm.