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Considerations for a European animal welfare standard to evaluate adverse phenotypes in teleost fish
Author(s) -
Bert Bettina,
Chmielewska Justyna,
Bergmann Sven,
Busch Maximilian,
Driever Wolfgang,
FingerBaier Karin,
Hößler Johanna,
Köhler Almut,
Leich Nora,
Misgeld Thomas,
Nöldner Torsten,
Reiher Annegret,
Schartl Manfred,
SeebachSproedt Anja,
Thumberger Thomas,
Schönfelder Gilbert,
Grune Barbara
Publication year - 2016
Publication title -
the embo journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.484
H-Index - 392
eISSN - 1460-2075
pISSN - 0261-4189
DOI - 10.15252/embj.201694448
Subject(s) - biology , fish <actinopterygii> , phenotype , zoology , fishery , genetics , gene
The EU Directive on the use animals in research requires scientists to assess and document pain, distress or lasting harm of genetically modified animals. This article proposes a detailed protocol and guidelines for assessing adverse phenotypes in teleost fish, an important model organism for biomedical research.