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Objective Eucalyptus camaldulensis  is recognized to be one of the major introduced eucalypts, the plant extracts possess a wide range of phytochemicals, which are accountable for its antioxidant and pharmacological activities. The extraction efficiency of such chemical compounds is influenced by the applied extraction conditions. To test the effect of solvent type on the yield of phenolics and antioxidants from  E. camaldulensis , seeking for an optimization of the extraction process. Method Dry powders of four plant organs were extracted by some organic solvents besides water. The total phenolic content was detected in the crude extracts of leaf, bud, empty capsule and seed, and was further characterized by GC-MS. Results Acetone-water mixtures yielded high amounts of phenolic compounds with parallel antioxidant activities, correlation coefficients were significant (0.696–0.998). Bud and capsule are first accredited for their antioxidant potentials. The GC-MS analysis revealed the abundance of most detected phenolic constituents in the plant seed. Discussion Acetone-water is a successful and appropriate mixture for the extraction of phenolic compounds from  E. camaldulensis . It could give better yields and enhance the biological activities of its corresponding extracts. Conclusion The accurate choice of an extraction solvent has a great influence on the yields of phenolics.

Acetone-water mixture is a competent solvent to extract phenolics and antioxidants from four organs of Eucalyptus camaldulensis