English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Tools annual

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Presents the access of premium content as premium feature

Premium Content

Global: Zendy Plus annual

Global: Zendy Free Plan

Aim  Our study was aimed to compare two different laboratory methods used to measure serum sodium and serum potassium level i.e. between the indirect Ion Selective Electrode (ISE) based and Enzymatic based method in Beckman Coulter AU-480, USA, in serum samples.    Materials and methods  This was a cross sectional single center study carried out from September’16 to January’17 on 130 serum samples, to compare the result of serum sodium (S. Na + ) and serum potassium (S. K + ) level by indirect ISE and Enzymatic method in fully automated biochemistry analyzer (Beckman Coulter AU-480, USA).    Results  To validate new enzymatic method bias, CV% and correlation coefficient were measured for S. Na +  and S. K + . The study has drawn a considerable agreement for measurement of S. K +  level between two methods with mean ± SD of difference was 0.14 ± 0.22 (p = 0.2242), CV% 2.7% and r 2  value of 0.94, whereas disagreement for measurement of S. Na +  level with mean ± SD of difference was 2.38 ± 2.36 (p &lt; 0.01), CV% 0.5% and r 2  value of 0.82. Bias, CV% and correlation coefficient are acceptable for S. K + , whereas nonacceptable for S. Na +  level measurement as per Clinical Laboratory Improvement Amendments (CLIA) guidelines.    Conclusion  There was a good correlation in S. K +  between both methods whereas values were not correlated well with S. Na +  level. So, enzymatic method can be used as an alternative to indirect ISE method for estimation of S. K +  in small laboratories due to its cost effectiveness, but still intense workout is required for estimation of S. Na + .

turkish journal of biochemistry

Is spectrophotometric enzymatic method a cost-effective alternative to indirect Ion Selective Electrode based method to measure electrolytes in small clinical laboratories?