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Accuracy is essential for optical head-tracking in cranial radiotherapy. Recently, the exploitation of local patterns of tissue information was proposed to achieve a more robust registration. Here, we validate a ground truth for this information obtained from high resolution MRI scans. In five subjects we compared the segmentation accuracy of a semi-automatic algorithm with five human experts. While the algorithm segments the skin and bone surface with an average accuracy of less than 0.1 mm and 0.2 mm, respectively, the mean error on the tissue thickness was 0.17 mm. We conclude that this accuracy is a reasonable basis for extracting reliable cutaneous structures to support surface registration.

Tissue segmentation from head MRI: a ground truth validation for feature-enhanced tracking