Open AccessThe amide group and its preparation methods by acid-amine coupling reactions: an overviewOpen Access
Author(s)
Agudo-Álvarez Sandra,
Díaz-Mínguez Sandra S.,
Benito-Arenas Raúl
Publication year2024
Publication title
pure and applied chemistry
Resource typeJournals
PublisherDe Gruyter
The amide bond is one of the most important structural units in nature, as it is part of the backbone of peptides and natural proteins, as well as some essential amino acids, DNA, RNA, hormones, or vitamins found in the body. Furthermore, this bond is significant in the pharmaceutical industry due to its presence in the structure of numerous APIs contained in drugs. This paper reviews the most important methods collected in the bibliography for the preparation of this moiety.
Keyword(s)Amides, benzotriazole, carbodiimides, guanidinium, uronium, VCCA-2023
Language(s)English
SCImago Journal Rank0.439
H-Index149
eISSN1365-3075
pISSN0033-4545
DOI10.1515/pac-2023-1104
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