Open AccessThe Sequence Effect in <italic>De Novo</italic> Parkinson’s Disease
Author(s) -
Suk Yun Kang,
Toshiaki Wasaka,
Ejaz A. Shamim,
Sungyoung Auh,
Yoshino Ueki,
Nguyet Dang,
Mark Hallett
Publication year - 2011
Publication title -
journal of movement disorders
Language(s) - English
Resource type - Journals
eISSN - 2093-4939
pISSN - 2005-940X
DOI - 10.14802/jmd.11006
Subject(s) - slowness , medicine , parkinson's disease , statistical significance , sequence (biology) , disease , genetics , physics , quantum mechanics , biology
The sequence effect (SE) in Parkinson's disease (PD) denotes progressive slowness in speed or progressive decrease in amplitude of repetitive movements. It is a well-known feature of bradykinesia and is considered unique in PD. Until now, it was well-documented in advanced PD, but not in drug-naïve PD. The aim of this study is to know whether the SE can also be measured in drug-naïve PD.