Open AccessMean Arterial Pressure Goal in Critically Ill Patients: A Meta-Analysis of Randomized Controlled Trials
Author(s) -
Sauradeep Sarkar,
Sahib Singh,
Amit Rout
Publication year - 2022
Publication title -
journal of clinical medicine research
Language(s) - English
Resource type - Journals
eISSN - 1918-3011
pISSN - 1918-3003
DOI - 10.14740/jocmr4702
Subject(s) - medicine , mean arterial pressure , meta analysis , early goal directed therapy , confidence interval , intensive care unit , randomized controlled trial , mechanical ventilation , critically ill , subgroup analysis , intensive care , relative risk , septic shock , intensive care medicine , blood pressure , sepsis , heart rate , severe sepsis
Current guidelines recommend targeting a mean arterial pressure (MAP) goal of 65 mm Hg or more in critically ill medical patients. Prospective studies have shown that a higher MAP goal can improve survival and decrease end-organ damage. However, randomized controlled trials (RCTs) have failed to show similar results. Thus, we performed this meta-analysis to evaluate whether a high MAP goal compared to a standard or low MAP goal will improve clinical outcomes in critically ill medical patients.