Open AccessToxic Epidermal Necrolysis-Like Lupus Erythematous Presentation Following SARS-CoV-2 Infection
Author(s) -
Ana Luísa Nunes,
Leonor Simoes,
Carolina Figueiredo,
Rúben Carvalho,
Jandira Lima,
Rui M Santos
Publication year - 2022
Publication title -
journal of medical cases
Language(s) - Uncategorized
Resource type - Journals
eISSN - 1923-4163
pISSN - 1923-4155
DOI - 10.14740/jmc3880
Subject(s) - medicine , toxic epidermal necrolysis , immunology , pathogenesis , systemic lupus erythematosus , disease , autoimmune disease , cytokine storm , dermatology , infectious disease (medical specialty) , covid-19 , pathology , antibody
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that affects multiple organs. Infectious agents have been implicated in the pathogenesis of SLE. The emergent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) induces a pro-inflammatory cytokine storm and has been linked to autoimmune phenomena, which can lead to the onset of autoimmune diseases. We report the case of a 70-year-old patient who developed a toxic epidermal necrolysis (TEN)-like subacute cutaneous lupus (SCL) as a severe presentation of SLE, 1 month after SARS-CoV-2 infection. After excluding other causes of SLE, treatment was initiated with a successful outcome.