Open AccessEosinophilia With Hepatic Mass and Abnormal Liver Function Tests: An Unusual Presentation of Chronic Myeloid Leukemia
Author(s) -
Neeraja Yerrapotu,
Susmitha Edappallath,
Mohammad Jarrar,
Caroline Hamm,
Pat A. Allevato,
Ali Gabali,
Indryas Woldie
Publication year - 2020
Publication title -
journal of medical cases
Language(s) - English
Resource type - Journals
eISSN - 1923-4163
pISSN - 1923-4155
DOI - 10.14740/jmc3513
Subject(s) - medicine , basophilia , monocytosis , eosinophilia , myeloid leukemia , pathology , eosinophilic , myeloproliferative neoplasm , myeloid , philadelphia chromosome , immunology , bone marrow , gene , chromosomal translocation , biology , biochemistry , myelofibrosis
Chronic myeloid leukemia (CML) is a chronic myeloproliferative neoplasm characterized by excess granulocytes at different stages of maturation and the presence of BCR-ABL1 fusion gene or Philadelphia chromosome. Absolute eosinophilia, basophilia, and monocytosis are not uncommon in CML. However, a rare entity called eosinophilic variant of CML (eoCML) can present with eosinophilia without excess neutrophils or basophils. Here, we report a rare and unusual case of eoCML presenting as a liver mass with abnormal liver function tests, which has not been reported in the literature so far.