Open AccessSARS-CoV-2-Induced Severe Immune Thrombocytopenic Purpura
Author(s) -
Aurelien Gonze,
Colin Hannesse,
Nathalie Coppens,
Helene Vellemans,
Guy Maury
Publication year - 2020
Publication title -
journal of medical cases
Language(s) - Uncategorized
Resource type - Journals
eISSN - 1923-4163
pISSN - 1923-4155
DOI - 10.14740/jmc3481
Subject(s) - medicine , thrombocytopenic purpura , platelet , immune system , coronavirus , immunology , covid-19 , purpura (gastropod) , thrombotic thrombocytopenic purpura , immune thrombocytopenia , disease , gamma globulin , virology , antibody , infectious disease (medical specialty) , outbreak , ecology , biology
Hematologic changes are common in coronavirus infections, including lymphopenia and thrombocytopenia. Thrombocytopenia was frequent during the severe acute respiratory syndrome coronavirus (SARS-CoV) in 2002 - 2003. The mechanisms involved in platelet deficiency are unclear. Many viruses are known to trigger immune thrombocytopenic purpura (ITP), but the disease is rarely described in association with coronavirus. We describe the case of acute ITP associated with coronavirus disease 19 (COVID-19) in an 86-year-old woman. Intravenous gamma-globulin and corticosteroids were effective on platelet count evolution.