Open AccessIs the Use of Proton Pump Inhibitors a Predisposing Factor for Pyogenic Liver Abscesses?
Author(s) -
Ahmed Elfiky,
Mira Alsheikh,
Jeff Hosry,
Anum Aqsa,
Ahmad Abou Yassine,
Liliane Deeb
Publication year - 2021
Publication title -
gastroenterology research
Language(s) - English
Resource type - Journals
eISSN - 1918-2813
pISSN - 1918-2805
DOI - 10.14740/gr1404
Subject(s) - pyogenic liver abscess , medicine , liver abscess , odds ratio , gastroenterology , abscess , proton pump inhibitor , univariate analysis , population , liver disease , surgery , multivariate analysis , environmental health
Proton pump inhibitors (PPIs) increase gastric pH by reducing acid production. The resulting alkaline milieu in the stomach increases the risk of bacterial translocation. This study aimed to investigate if there is a correlation between PPI use and developing pyogenic liver abscesses.