Open AccessLABORATORY DIAGNOSTICS OF MALE INFERTILITY. BIOMARKERS. PART I
Author(s) -
Zh. Yu. Sapozhkova,
G. A. Milovanova,
Olga I. Patsap
Publication year - 2021
Publication title -
laboratornaâ i kliničeskaâ medicina. farmaciâ
Language(s) - English
Resource type - Journals
ISSN - 2712-9330
DOI - 10.14489/lcmp.2021.01.pp.057-068
Subject(s) - infertility , male infertility , medicine , unexplained infertility , gynecology , semen , diagnostic test , reproductive medicine , medical physics , biology , andrology , pregnancy , pediatrics , genetics
Currently, clinical laboratory diagnostics of male infertility is an integral part of the diagnostic process in the field of reproductive medicine. This review provides information about novel and traditional immunological, cellular, biochemical and other markers of human semen, which are used in the complex laboratory diagnostics of male infertility. Unfortunately, at present, due to the lack of updated clinical guidelines for male and female infertility diagnostics, uninformative algorithms and incompatible assessment criteria are increasingly used. This situation leads to controversial discussions, where the diagnostic functions of laboratory tests and markers are questioned. That is why the constant search is needed for innovative diagnostic approaches aimed at in-depth study of the pathogenesis of male infertility and subfertility.