Open AccessDynamic interphase tensiometry of the urine is a method of early diagnosis of diabetic nephropathy
Author(s) -
O.V. Sinyachenko,
V. N. Kazakov,
M. V. Zyablitseva,
E. D. Yegudina,
V. B. Fainerman,
E. D. Yakubenko
Publication year - 2001
Publication title -
problemy èndokrinologii
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.124
H-Index - 5
eISSN - 2308-1430
pISSN - 0375-9660
DOI - 10.14341/probl11285
Subject(s) - urine , diabetic nephropathy , medicine , interphase , urology , nephropathy , urinary system , endocrinology , diabetes mellitus , biology , genetics
Dynamic surface tension (ST) of the urine was studied in 58 diabetics without manifest clinical laboratory symptoms of nephropathy by means of computer tensiometers MRT1 and MRT2 (Lauda, Germany). A significant decrease in ST values in the median and longer surface life spans and of the angle of tensiogram curve inclination was revealed. Changes in ST parameters ( M + 3m) of albumin (in 24.1%), p2 microglobulin (in 31%), and fibronectin (in 8.6%). Dynamic interphase tensiometry of the urine can be used for early diagnosis of diabetic nephropathy and monitoring the efficiency of treatment.