Open AccessInfertile marriage in patients with diabetes mellitus
Author(s) -
I. I. Vityazeva,
S. V. Bogolyubov,
Irena Ilovayskaya,
Н. П. Макарова,
Alesya Gennad'evna L'vova
Publication year - 2009
Publication title -
saharnyj diabet
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.155
H-Index - 12
eISSN - 2072-0378
pISSN - 2072-0351
DOI - 10.14341/2072-0351-5695
Subject(s) - medicine , diabetes mellitus , endocrine system , infertility , oxidative stress , hormone , endocrinology , reproductive system , pregnancy , biology , genetics
Diabetes mellitus affects reproductive function at different levels both in men and women. It disturbs regulation of the hypothalamo-pituitary axisand impairs gonadal endocrine function at the cellular level due to direct effect of acute and/or chronic hyperglycemia, oxidative stress and microvascularcomplications. Moreover, central dysregulation aggravates hormonal disorders. Assisted reproductive technologies (ART) provide a tool for thetreatment of male and female infertility in diabetic patients although many aspects of its application await in-depth studies.