Open AccessSINTESIS XANTON DARI ASAM 2-PHENOXYBENZOIC ACID SEBAGAI BAHAN DASAR OBAT MALARIA BARU
Author(s) -
Amanatie Amanatie,
Jumina Jumina,
Mustofa Mustofa,
Muhammad Hanafi
Publication year - 2013
Publication title -
jurnal kimia terapan indonesia
Language(s) - English
Resource type - Journals
eISSN - 2527-7669
pISSN - 0853-2788
DOI - 10.14203/jkti.v15i2.108
Subject(s) - xanthone , yield (engineering) , sulfuric acid , chemistry , stereochemistry , organic chemistry , materials science , metallurgy
Synthesis of xanthone was conducted from the raw material of 2-phenoxybenzoic acid through acid-catalyzed-cyclization. The product was characterized using UV- Vis, 1 13 d FT-IR, H-NMR, C-NMR, an LC-MS Cyclization of 2-phenoxybenzoic acid using sulfuric acid catalyt gave xanthone in 86.11 % yield. These compounds as the basis of new malaria drugs.Keywords 2-phenoxybenzoic acid, Synthesis, Xanthone, Characterized.