Open AccessObservation of cone and rod photoreceptors in normal subjects and patients using a new generation adaptive optics scanning laser ophthalmoscope
Author(s) -
David Merino,
Jacque L. Duncan,
Pavan Tiruveedhula,
Austin Roorda
Publication year - 2011
Publication title -
biomedical optics express
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.362
H-Index - 86
ISSN - 2156-7085
DOI - 10.1364/boe.2.002189
Subject(s) - scanning laser ophthalmoscopy , achromatopsia , adaptive optics , optics , ophthalmology , ophthalmoscopy , retinal , medicine , physics
We demonstrate the capability of a new generation adaptive optics scanning laser ophthalmoscope (AOSLO) to resolve cones and rods in normal subjects, and confirm our findings by comparing cone and rod spacing with published histology measurements. Cone and rod spacing measurements are also performed on AOSLO images from two different diseased eyes, one affected by achromatopsia and the other by acute zonal occult outer retinopathy (AZOOR). The potential of AOSLO technology in the study of these and other retinal diseases is illustrated.