Open AccessSystemic lupus erythematosus and antineutrophil cytoplasmic antibody-associated vasculitis overlap syndrome in a 77-year-old man: A case report
Author(s) -
Zi-Gan Xu,
Wei-Long Li,
Xi Wang,
Shuyuan Zhang,
Yingwei Zhang,
Xing Wei,
Chundi Li,
Ping Zeng,
Shaodong Luan
Publication year - 2021
Publication title -
world journal of clinical cases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.368
H-Index - 10
ISSN - 2307-8960
DOI - 10.12998/wjcc.v9.i3.707
Subject(s) - medicine , anti neutrophil cytoplasmic antibody , vasculitis , antibody , dermatology , systemic lupus erythematosus , overlap syndrome , immunology , pathology , disease
Systemic lupus erythematosus (SLE) and antineutrophil cytoplasmic antibody-associated vasculitis (AAV) are classically thought to cause renal impairment and small vessel vasculitis with different pathophysiologies. Their overlap constitutes a rare rheumatologic disease. To date, only dozens of such cases with biopsy-proven glomerulonephritis have been reported worldwide typically in women of childbearing age. Here, we present a unique clinical case due to its rarity and individualized treatment of a Chinese man in his eighth decade of life.