Open AccessAcquired haemophilia in patients with malignant disease: A case report
Author(s) -
Veronika Krašek,
Aleša Kotnik,
Hana Zavrtanik,
Jasna Klen,
Samo Zver
Publication year - 2021
Publication title -
world journal of clinical cases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.368
H-Index - 10
ISSN - 2307-8960
DOI - 10.12998/wjcc.v9.i10.2409
Subject(s) - medicine , haemophilia , disease , dermatology , surgery
Acquired haemophilia is a rare coagulation disorder characterized by autoantibodies against coagulation factor VIII leading to severe and potentially life-threatening haemorrhages. The underlying disorder causing the development of an autoimmune phenomenon is not always known, but 10%-15% could be linked to malignancies. Patients with cancer who require surgical resection represent a treatment challenge not solely due to increased risk of bleeding but also due to adverse events of immunosuppressive therapy.