Open AccessDurable response to pulsatile icotinib for central nervous system metastases from EGFR-mutated non-small cell lung cancer: A case report
Author(s) -
Huiying Li,
Yu Xie,
Tingting Yu,
Yongjuan Lin,
Zhenyu Yin
Publication year - 2020
Publication title -
world journal of clinical cases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.368
H-Index - 10
ISSN - 2307-8960
DOI - 10.12998/wjcc.v8.i2.370
Subject(s) - medicine , central nervous system , lung cancer , epidermal growth factor receptor , oncology , cancer , lung , meningeal carcinomatosis , cerebrospinal fluid
Central nervous system (CNS) metastases are a catastrophic complication of non-small cell lung cancer (NSCLC), including brain and leptomeningeal carcinomatosis, and are always accompanied by a poor prognosis. Despite the continuous development of existing treatments, the therapy of CNS metastases remains challenging.