Open AccessEffective chemotherapy for submandibular gland carcinoma ex pleomorphic adenoma with lung metastasis after radiotherapy: A case report
Author(s) -
Zhiyuan Chen,
Yu Zhang,
Yan Yi Tu,
Wei Zhao,
Mei Li
Publication year - 2019
Publication title -
world journal of clinical cases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.368
H-Index - 10
ISSN - 2307-8960
DOI - 10.12998/wjcc.v7.i6.792
Subject(s) - medicine , radiation therapy , pleomorphic adenoma , carcinoma ex pleomorphic adenoma , chemotherapy , metastasis , carcinoma , submandibular gland , surgery , oncology , pathology , salivary gland , cancer
Only a few cases of carcinoma ex pleomorphic adenoma arising in the submandibular gland have ever been reported, all with a poor prognosis. The standard treatment for salivary gland carcinoma ex pleomorphic adenoma is surgical resection combined with postoperative radiotherapy, but the necessity of chemotherapy as well as the most appropriate treatment regimen for patients with distant metastasis after radiotherapy remains controversial.