Open AccessEfficacy of EGFR-TKI sequential therapy in patients with EGFR exon 19 insertion-positive non-small-cell lung cancer: A case report
Author(s) -
Binbin Shan,
Yuan Li,
Chang Zhao,
Xiaoqin An,
Quan-Mao Zhang
Publication year - 2022
Publication title -
world journal of clinical cases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.368
H-Index - 10
ISSN - 2307-8960
DOI - 10.12998/wjcc.v10.i6.1883
Subject(s) - medicine , epidermal growth factor receptor , exon , lung cancer , oncology , mutation , tyrosine kinase , targeted therapy , cancer research , tyrosine kinase inhibitor , cancer , gene , receptor , genetics , biology
Insertions in exon 19 in the epidermal growth factor receptor gene (EGFR) is a rarely seen mutation in non-small cell lung cancer. These patients have been effectively treated with sequential EGFR tyrosine kinase inhibitors (TKIs).