Open AccessExploring the Genetic Associations Between the Use of Statins and Alzheimer's Disease
Author(s) -
Jibeom Lee,
Suhyeon Park,
Yumin Kim,
Hyun Min Kim,
ChangMyung Oh
Publication year - 2022
Publication title -
journal of lipid and atherosclerosis
Language(s) - English
Resource type - Journals
eISSN - 2288-2561
pISSN - 2287-2892
DOI - 10.12997/jla.2022.11.2.133
Subject(s) - statin , kegg , dementia , alzheimer's disease , gene , stem cell , disease , bioinformatics , gene expression , medicine , biology , cancer research , transcriptome , genetics
Alzheimer's disease (AD) is the most common cause of dementia. The statins have shown beneficial effects on cognitive functions and reduced the risk of dementia development. However, the exact mechanisms of statin effects in AD are not yet fully understood. In this study, we aimed to explore the underlying mechanisms of statin on AD.