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Adjuvant chemotherapy has been the standard of care for patients with early breast cancer (EBC) on the basis of early National Surgical Adjuvant Breast and Bowel Project studies. In the 2000s, it was realized that most patients with EBC, especially those with hormonepositive and node-negative disease are being overtreated, and clinical and histologic features may not be sufficient tomake decisions regarding adjuvant therapy.

Oncotype DX: Where Does It Stand in India?